Proteins are the tiny machines that keep our cells running, and how long they last in the cell often determines how well they ...

In people destined to get Alzheimer's in their mid-40s, one protein can delay the onset of the disease by about 20 years.

Houston Methodist scientists have uncovered an unexpected side of a protein best known for its link to brain diseases. The ...

A hallmark of Parkinson’s disease is the buildup of Lewy bodies — misfolded clumps of the protein known as alpha-synuclein. Long before Lewy bodies form, alpha-synuclein can interfere with neurons’ ...

Most mutations that cause disease by swapping one amino acid out for another do so by making the protein less stable, according to a major study of human protein variants that was published in Nature ...

A mutation in the TDP-43 protein reduces the viability of motor neurons without triggering protein clumps, researchers found.

A protein long studied for its role in amyotrophic lateral sclerosis and frontotemporal dementia now appears to serve a ...

Researchers have discovered a new way to increase a key brain protein damaged in Rett syndrome, a rare genetic disorder that affects thousands of children worldwide. Early studies in mice and ...

One of the symptoms of schizophrenia is difficulty incorporating new information about the world. This can lead patients to ...