For decades, the central dogma of molecular biology—DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease. This model explained ...

Although there are striking differences between the cells that make up your eyes, kidneys, brain and toes, the DNA blueprint for these cells is essentially the same. Where do those differences come ...

Two separate laboratory breakthroughs have produced RNA molecules that can build copies of themselves or assemble functional structures without any help from proteins or DNA. These results offer the ...

In a recent study published in the Journal of American Medical Association (JAMA) Oncology, researchers from California investigated the diagnostic outcomes of concurrent sequencing of ...

Gene expression is linked to RNA transcription, which cannot happen without RNA polymerase. However, this is where the similarities between prokaryote and eukaryote expression end. Central to the ...

From vaccines and diagnostics to emerging gene-based therapies, RNA molecules are now central to modern medicine. But as their use continues to grow, so does a fundamental challenge: producing RNA ...