An international research team has discovered a previously unknown mechanism that plays a key role in the signaling pathways involved in programmed cell death. The team identified the protein HERC4 as ...

A new review in Biogerontology argues that the Hippo–YAP/TAZ signalling pathway acts as a central hub linking brain ageing, ...

Gene therapies are used to treat many different blood disorders. However, blood stem cells often fail to achieve their full ...

New research shows that inhibiting the FGFR signaling pathway reduces T cell exhaustion and repolarizes macrophages, ...

The evolving landscape of peptide-based inquiry continues to uncover fragments that diverge meaningfully from their parent molecules, not by replicating their ...

A protein known as p53 is, of all tumor suppressors in human cancer, the most frequently altered by gene mutations.

Blood stem cells are rare cells in the bone marrow that produce the blood and immune cells needed throughout life, thus ...

A small protein known as p11 may play a much broader role in cellular signaling than previously thought. Researchers at ...

Autophagy is essentially the 'rubbish collection' of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest ...

Explore how oncogenes and signaling pathways converge and diverge in cancer, shaping diagnostic and therapeutic strategies for personalized interventions. This convergence is accompanied by ...