Researchers at the RIKEN Center for Biosystems Dynamics Research (BDR) have identified key changes to both chromosome structure and gene expression that affect stem cell function during aging. Using ...
Genome-wide chromatin accessibility profiling reveals how myelodysplastic syndrome (MDS) stem cells progressively lose normal stem-cell features and acquire myeloid progenitor-like characteristics.
Every cell in a body contains the same genetic sequence, yet each cell expresses only a subset of those genes. These cell-specific gene expression patterns, which ensure that a brain cell is different ...
A team led by Professor Inkyung Jung from the Department of Biological Sciences at KAIST, working with Professor Yarui Diao’s group, has published a new single-cell method called scHiCAR that ...
Researchers from the University of Chicago (IL, USA) have reported that unstable, or ‘noisy’, chromatin enables cells to take on different roles in the body. This flexibility can support the immune ...
The framework of CASHeart. (A) Overview of the data collection and data processing workflow in the CASHeart Database. (B) Introduction to the main interfaces of the CASHeart website. The human heart ...